CASE REPORTS   

Minerva Stomatologica 2007 January-February;56(1-2):73-9

Copyright © 2006 EDIZIONI MINERVA MEDICA

language: English, Italian

Traumatic ulcerative granuloma with stromal eosinophilia of the oral mucosa: histological and immunohistochemical analysis of three cases

Pilolli G. P. ¹, Lucchese A. ¹, Scivetti M. ¹, Maiorano E. ², Favia G. ¹

¹ Department of Odontostomatology and Surgery University of Bari, Bari, Italy 2 Department of Pathology and Genetics University of Bari, Bari, Italy

Traumatic ulcerative granuloma with stromal eosinophilia is an ulcerated oral lesion which pathogenesis is still unclear. Clinically, this disease is characterized by the presence of chronic ulcerative lesions with elevated and indurated borders in the oral mucosa. It usually develops rapidly and persists for several weeks or months, it presents mainly on the tongue but other areas such as gingival, cheek and vestibular mucosa may also be involved. We report three cases showing their clinical, histological and immunohistochemical analysis. In this study the authors underline the importance of a correct differential diagnosis and monitoring of these patients in order to prevent the development of possible serious complications.