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Minerva Stomatologica 2005 March;54(3):153-60

Copyright © 2005 EDIZIONI MINERVA MEDICA

language: English, Italian

Clinical evaluation of antibiotic prophylaxis before endodontic treatment of necrotic teeth

Contardo L., Meneguzzi E., Cadenaro M., Di Lenarda R.


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Aim. The efficacy of antibiotic prophylaxis before endodontic treatment of necrotic teeth in the prevention of post-treatment flare-up pain and swelling was evaluated.
Methods. A total of 47 teeth with diagnosis of pulpal necrosis were selected in 39 patients, independently from the pre-operative symptomatology (painful or asymptomatic). Teeth were randomly divided into 2 groups. The first group (n=23) was given an antibiotic prophylaxis with 2 g amoxicillin 1 h before every appointment; the second group (n=24) did not receive any treatment (control group). The endodontic therapy was performed by shaping canals using the crown-down technique with hand devices, 5% sodium hypochlorite irrigations and 2 intermediate medications with Ca(OH)2. Obturation was performed using randomly the vertical obturation technique or the no-stop wave technique. At the end of each appointment a questionnaire was given to each patient. The patient had to indicate if pain (absent, light, mild, severe) or swelling were present at 4, 8, 12, 24 h after every appointment. Data were statistically analysed with the Mann-Whitney, Wilcoxon and x2 test.
Results. Only a case of flare-up pain and swelling was found in a patient of the study group. The statistical analysis showed that there were no significant differences between the 2 groups.
Conclusion. An accurate endodontic treatment of necrotic canals is sufficient to guarantee an adeguate control of post-treatment pain, with no need of antibiotic prophylaxis.

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