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Minerva Respiratory Medicine 2021 December;60(4):131-5

DOI: 10.23736/S2784-8477.21.01985-9

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

Analysis of survival in lung transplantation: simple diagnostic tests in a new “SELeCT” Score used as prognostic tool. Results from a single center cohort study

Filippo PATRUCCO 1 , Carlo ALBERA 1, 2, Elisa CLIVATI 1, Massimo BOFFINI 3, Mauro RINALDI 3, Cristina COSTA 4, Rossana CAVALLO 4, Paolo SOLIDORO 1, 2

1 Unit of Respiratory Diseases, Cardiovascular and Thoracic Department, Città della Salute e della Scienza, University of Turin, Turin, Italy; 2 Department of Medical Sciences, University of Turin, Turin, Italy; 3 Unit of Cardiac Surgery, Cardiovascular and Thoracic Department, Città della Salute e della Scienza, University of Turin, Turin, Italy; 4 Division of Virology, Department of Public Health and Pediatrics, Città della Salute e della Scienza, University of Turin, Turin, Italy



BACKGROUND: There are few validated scores evaluating outcomes of lung transplanted patients based on donor or recipient characteristic before or at the time of transplantation.
METHODS: In our study we evaluated a new, and easy to use, 5-item score on survival of patients who underwent lung transplantation. It was called SELeCT Score and was based on clinical, laboratoristic and radiological findings recorded at each observation.
RESULTS: We found higher scores in case of unscheduled observations and an inverse correlation with overall survival rate, even excluding patients who died within 60 days. We identified a threshold of 2 points as significant to predict patients’ survival. Fungal and bacterial infections show scores higher than acute rejections and CMV and other viral infections.
CONCLUSIONS: SELeCT Score could represent a useful prognostic tool in guiding clinical choices, demonstrating that more compromised patients (routinely evaluated with clinic, laboratory test and radiological images) had a worse outcome, and that it could be important at least as much as the identification of the etiology.


KEY WORDS: Lung transplantation; Pulmonary medicine; Survival

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