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  TREATING RESPIRATORY DISEASE 

Minerva Pneumologica 2013 June-September;52(2-3):77-88

Copyright © 2013 EDIZIONI MINERVA MEDICA

language: English

Endoscopic lung volume reduction: an updated review

Schuhmann M., Kaukel P., Eberhardt R.

Thoraxklinik at the University of Heidelberg Heidelberg, Germany


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Emphysema with significant hyperinflation is a severely debilitating disease with only limited treatment options. Endoscopic lung volume reduction has now been used in select groups for several years and has shown promising results. Careful patient selection and assessment of emphysema heterogeneity and distribution prior to any intervention is important to achieve the best possible outcome. Blocking and non-blocking devices are available and we review the data available as well as the current indications for these treatment. To date the best data available is for endobronchial valves, all other devices have only been published with small patient numbers. In the future randomized trials in larger patient groups are required to decide which emphysema phenotypes benefit the most, to address safety issues and to minimize complications by preselecting the most appropriate patient for each technique.

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