Home > Journals > Minerva Pneumologica > Past Issues > Minerva Pneumologica 2002 September;41(3) > Minerva Pneumologica 2002 September;41(3):113-22

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Reprints
Permissions

 

REVIEWS   

Minerva Pneumologica 2002 September;41(3):113-22

Copyright © 2002 EDIZIONI MINERVA MEDICA

language: Italian

Exhaled nitric oxide after inhalation of isotonic and hypotonic solutions

Maniscalco M., Sofia M.


PDF


Up to few years ago nitric oxide (NO), produced by several cells in the respiratory tract, was considered only a noxious gaseous component of environmental pollution it is involved in important biological roles including the regulation of blood flow, platelet function, neurotransmission and immunity. NO measurement from exhaled air has been suggested as a useful tool in monitoring inflammatory diseases in the human airways. NO detected in the airways may be influenced by several direct and indirect challenges, such as inhalation of solutions at different osmolarity. After a short review of NO chemical-physical property, production and physiology, the potential role of modifications of airway environment (osmolarity, pH, active and passive smoke) on mechanisms of NO synthesis and the relative physiopathological implications will be discussed.

top of page