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SPECIAL ARTICLE  GROWTH AND PUBERTY IN CHILDREN 

Minerva Pediatrica 2020 December;72(6):491-500

DOI: 10.23736/S0026-4946.20.05970-8

Copyright © 2020 EDIZIONI MINERVA MEDICA

language: English

Precocious puberty

Mariam GANGAT , Sally RADOVICK

Unit of Pediatric Endocrinology, Department of Pediatrics, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA



Precocious puberty (PP) is a common reason for referral to pediatric endocrinology clinics, with a strong female predominance. PP is a broad term encompassing benign variants of normal development, gonadotropin-dependent precious puberty (GDPP), and gonadotropin-independent precocious puberty (GIPP). This article reviews the definitions, physiology, clinical presentation, evaluation and treatment of these conditions.


KEY WORDS: Puberty, precocious; Gonadotropin-releasing hormone; Adrenarche

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