Home > Journals > Minerva Pediatrica > Past Issues > Articles online first > Minerva Pediatrica 2020 May 15

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Publication history
Reprints
Permissions
Cite this article as

 

 

Minerva Pediatrica 2020 May 15

DOI: 10.23736/S0026-4946.20.05750-3

Copyright © 2020 EDIZIONI MINERVA MEDICA

language: English

Colectomy and health-related quality of life in children with ulcerative colitis

Valeria DIPASQUALE 1, Maria A. CATENA 1, Lucia PAIANO 2, Giuseppe TRIMARCHI 3, Carmelo ROMEO 2, Giuseppe NAVARRA 4, Girolamo MATTIOLI 5, Claudio ROMANO 1

1 Pediatric Gastroenterology and Cystic Fibrosis Unit, Department of Human Pathology in Adulthood and Childhood "G. Barresi", University of Messina, Messina, Italy; 2 Pediatric Surgery Unit, Department of Human Pathology in Adulthood and Childhood “G. Barresi", University of Messina, Messina, Italy; 3 Department of Economy, University of Messina, Messina, Italy; 4 General Surgery Unit, Department of Human Pathology in Adulthood and Childhood “G. Barresi", University of Messina, Messina, Italy; 5 Pediatric Surgery Unit, Giannina Gaslini Research Institute and Children Hospital, Genova, Italy


PDF


BACKGROUND: Restorative proctocolectomy and ileal pouch-anal anastomosis (IPAA) is the recommended elective surgery for children with ulcerative colitis (UC). The aim of this study was to evaluate functional and long-term health-related quality of life (HRQoL) outcomes of surgery in paediatric patients with UC.
METHODS: We reviewed the hospital records of all paediatric patients who had undergone surgery for UC between January 2009 and December 2016 in the Units of Paediatric Gastroenterology and Surgery, of both the University Hospital of Messina, and the Gaslini Children’s Hospital of Genoa. Surgical treatment was represented by restorative proctocolectomy and laparoscopic IPAA. Patients and parents were interviewed by telephone before and after surgery and responded to the modified IMPACT III questionnaire about health outcomes and HRQoL. The questionnaire was scored on a five-point scale with higher scores indicating a better HRQoL. The total score ranged from 35 (worst HRQoL) to 175 (best HRQoL).
RESULTS: Data were obtained in 30 patients (16 males), with a median age of 12 (range 3- 16). The median amount of time elapsed after the operation was 3 years (range 1-4.5). Preoperative scores were very low in all 4 domains of the questionnaire. Postoperatively, HRQoL measures improved significantly (p<0.05), on symptoms, school attendance, social activities, and emotional aspects. Overall, nearly all were completely satisfied with the outcome of surgery.
CONCLUSIONS: Our data confirmed that surgical treatment improves the overall HRQoL in paediatric patients with UC.


KEY WORDS: Quality of life; Surgery; Colectomy; Ulcerative colitis; Paediatrics

top of page