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MINERVA PEDIATRICA

A Journal on Pediatrics, Neonatology, Adolescent Medicine,
Child and Adolescent Psychiatry


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Minerva Pediatrica 2017 Sep 15

DOI: 10.23736/S0026-4946.17.05049-6

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: English

Clinical study of Vitamin A combined with Vitamin B in prevention and treatment of anemia in premature infants

Changhong CHAI 1, Xiuhua WANG 2, Chunlei HOU 1

1 Department of Pediatrics, Daqing Longnan Hospital, Daqing, Heilongjiang, China; 2 Department of Pediatrics, Daqing Oilfield General Hospital, Daqing, Heilongjiang, China


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BACKGROUND: We explored the clinical efficacy of vitamin A combined with vitamin B in the prevention and treatment of premature infants with anemia.
METHODS: 150 cases of premature infants were divided into three groups. Vitamin A combined with recombinant human erythropoietin (group A), vitamin B combined with recombinant human erythropoietin (group B), vitamin A combined with vitamin B combined with recombinant human erythropoietin treatment (recorded as group C). Levels of serum ferritin (SF), hemoglobin (Hb), hematocrit (Hct) and reticulocyte (Ret) in the serum of children before and after treatment were compared with those of three different treatments.
RESULTS: After treatment, the levels of SF, Hb and Ret in group C were higher than those in group A and B, and the level of Hct in group C was lower than that in group A and B (p<0.05) There was no significant difference in SF, Hb, Hct and Ret between the two groups (p>0.05). The ratio of blood transfusion in group C was lower than that in group A and B (p<0.05). There was no significant difference between the two groups (p>0.05).
CONCLUSIONS: Vitamin A combined with vitamin B can effectively prevent anemia in premature infants, which has important clinical significance.


KEY WORDS: Vitamin A - Vitamin B - Anemia of premature infants

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Publication History

Article first published online: September 15, 2017
Manuscript accepted: July 26, 2017
Manuscript received: July 16, 2017

Cite this article as

Chai C, Wang X, Hou C. Clinical study of Vitamin A combined with Vitamin B in prevention and treatment of anemia in premature infants. Minerva Pediatr 2017 Sep 15. DOI: 10.23736/S0026-4946.17.05049-6

Corresponding author e-mail

drchunleihou@hotmail.com