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Minerva Pediatrica 2019 April;71(2):150-8

DOI: 10.23736/S0026-4946.18.05449-X

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English

Enterovirus and parechovirus infections in children: differences in clinical presentation, mechanisms for meningitis without pleocytosis and mechanisms involved in the neurological outcome

Stephanie C. de CROM

Department of Pediatrics, Bravis Hospital, Roosendaal, The Netherlands



Enterovirus (EV) and Parechovirus (HPeV) are a frequent cause of infection in children. This review gives an overview of possible causes for differences in clinical presentation. EV and HPeV can cause a meningitis with or without pleocytosis. Different possible mechanisms for meningitis without pleocytosis are given. Little is known about the prognosis and long-term effects of EV and HPeV meningitis in children. Only some studies with a small number of children with EV or HPeV meningitis are reported. The different possible mechanisms involved in the neurological outcome after EV or HPeV meningitis will be discussed.


KEY WORDS: Enterovirus - Parechovirus - Child - Infection

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