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Minerva Pediatrica 2018 October;70(5):467-75

DOI: 10.23736/S0026-4946.18.05290-8

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English

Metabolic syndrome severity and lifestyle factors among adolescents

Linda X. WANG 1, Matthew J. GURKA 2, Mark D. DEBOER 1

1 Department of Pediatrics, University of Virginia, Charlottesville, VA, USA; 2 Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida, Gainesville, FL, USA



The continued rise of pediatric obesity globally has raised concerns for related sequalae. One marker of risk is the metabolic syndrome, a cluster of cardiovascular risk factors that is associated with future cardiovascular disease and type 2 diabetes. MetS has at its core visceral adipocytes exhibiting dysfunction as a result of excess fat content. MetS in children and adolescents is linked to unhealthy lifestyle practices such as sedentary lifestyles and excess consumption calories. As such, the optimal means of addressing MetS is targeting a decrease in adiposity through lifestyle modification, a decrease in MetS following increases in physical activity and improvements in the quality and content of food intake. Efforts remain needed in increasing motivation to these changes and maintaining adherence to avoid long-term sequelae.


KEY WORDS: Pediatric obesity - Metabolic syndrome - Life style

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