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Minerva Pediatrica 2013 June;65(3):341-7

Copyright © 2013 EDIZIONI MINERVA MEDICA

language: Italian

How to interpret the results of immunological tests for the diagnosis of tuberculosis in child

Remaschi G., Chiappini E., Bonsignori F., Mazzantini R., Galli L., De Martino M.

AOU Meyer, Dipartimento di Scienze per la Salute della Donna e del Bambino, Università di Firenze, Firenze, Italia


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New available immunologic tests for tuberculosis (TB) diagnosis are Interferon-gamma release assay (IGRA). In adults these tests showed a higher specificity than tuberculin skin test (TST) but their superior sensitivity compared to TST sensitivity has not been proved yet. In children, interpretation of results remains disputed, especially in those <5 years. Hereby we report the most recent literature data for use and interpretation of IGRA is results in children.

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