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Minerva Pediatrica 2010 December;62(6):605-7

Copyright © 2010 EDIZIONI MINERVA MEDICA

language: English

Mycoplasma pneumoniae: a possible trigger of kawasaki disease or a mere coincidental association? Report of the first four Italian cases

Vitale E. A., La Torre F., Calcagno G., Infricciori G., Fede C., Conti G., Chimenz R., Falcini F.

1 Department of Pediatrics, Rheumatology Unit, University of Messina, Messina, Italy; 2 Department of Pediatrics, Rheumatology Unit, University of Florence, Florence, Italy; 3 Department of Pediatrics, Ospedale Civile “Madonna del Soccorso”, S. Benedetto del Tronto, Ascoli Piceno, Italy


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Although epidemiological and clinical features strongly suggest an infectious cause, the etiology of Kawasaki disease (KD) still remains unknown. The hypothesis that bacterial toxins acting as superantigens could trigger the cascade of events leading to KD has been widely debated. We report four children with typical KD in whom a serological evidence of Mycoplasma pneumoniae infection was detected.

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