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Minerva Pediatrica 2004 April;56(2):161-6

Copyright © 2004 EDIZIONI MINERVA MEDICA

language: English

Pharmacological strategies in the idiopatic pulmonary fibrosis of children

Rigante D., Stabile A.


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Idiopathic pulmonary fibrosis is characterized by radiographically evident interstitial infiltrates and progressive dyspnea with rapid decline of overall lung functions. The clinical course of this disease is highly variable; however, its prognosis remains poor without adequate and prompt therapeutical support. Due to the fact that barely a quarter of patients responds to steroids alone, cytostatics are often prescribed simultaneously with low dose corticosteroids in the pediatric age too. Cytokine or anti-cytokine therapy and the role of new antifibrotic drugs are still at the experimental stage of definition and will be discussed in the following review.

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