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Minerva Ortopedica e Traumatologica 2019 June;70(2):112-5

DOI: 10.23736/S0394-3410.19.03918-3

Copyright © 2019 EDIZIONI MINERVA MEDICA

language: English

A report of a very rare isolated bone metastasis in the midfoot due to cervix cancer

Carlo PERISANO 1, Raffaele VITIELLO 1, 2 , Tommaso GRECO 1, 2, Luigi CIANNI 1, 2, Giulio MACCAURO 1, 2, Stefania SFREGOLA 1, 3, Marco GESSI 1, 3, Fabio MANCINO 1, 2

1 Area Invecchiamento, Ortopedia e Riabilitazione, Policlinico Universitario A. Gemelli IRCSS Foundation, Rome, Italy; 2 Sacred Heart Catholic University, Rome, Italy; 3 Department of Anatomical Histological Pathology, Policlinico Universitario A. Gemelli IRCSS Foundation, Rome, Italy



Acrometastases are intended as secondary localizations distal to elbow or knee. The usually are very rare (0.1% of all secondary localizations) and they are found in wide-spread disease even though they might be the first presentation of the disease. It is common sense to consider their dissemination through the vascular systemic system, that’s probably the reason why they are so rare since the foot’s bones are pore in red marrow. They usually manifest with intermittent pain, swallowing of the soft tissue, erythema and functional impairment. They can be misdiagnosed with inflammatory lesions, cysts, gout, ganglia, osteomyelitis, pyogenic granuloma, primary skin or bone and soft tissue tumors and tuberculous dactylitis. Since they are so rare there is not a standardized treatmen. The most frequent surgical treatment is amputation, when that is not possible palliation is the only alternative. The most frequent cancer that gives acrometastases is adenocarcinoma (lung, gastrointestinal and urogenital) but there are no reported cases of foot’s metastasis of clear cell uterine carcinoma. We report, to the best of our knowledge, the first case of secondary osteolytic lesion of the mid-foot from clear cell uterine carcinoma.


KEY WORDS: Foot; Neoplasm metastases; Uterine neoplasms

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