REVIEW  MUSCULOSKELETAL TISSUE INJURIES AND REGENERATION 

Minerva Orthopedics 2022 February;73(1):10-9

DOI: 10.23736/S2784-8469.21.04116-X

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

The management of post-traumatic bone defects: a systematic review

Giovanni VICENTI ¹ ✉, Guglielmo OTTAVIANI ¹, Davide BIZZOCA ¹, Massimiliano CARROZZO ¹, Filippo SIMONE ¹, Alessandro GROSSO ¹, Giacomo ZAVATTINI ¹, Rossella ELIA ², Michele MARUCCIA ², Giuseppe SOLARINO ¹, Biagio MORETTI ¹

¹ Section of Orthopedics, Department of Neuroscience and Organs of Sense, University of Bari Aldo Moro, Bari, Italy; ² Division of Plastic and Reconstructive Surgery, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy

INTRODUCTION: Large bone defects are commonly caused by severe traumas, pseudoarthrosis and tumors. Managing large bone defects remains a challenging problem, requiring complex and multidisciplinary treatment.
EVIDENCE ACQUISITION: We searched terms on PubMed, Google Scholar and the Cochrane library from inception until December 2020. The search strategy was a combination of medical, subjective and methodological keywords.
EVIDENCE SYNTHESIS: Several techniques have been described for the management of bone defects: intramedullary nailing, transosseus compression distraction osteosynthesis, Masquelet technique, bone grafting.
CONCLUSIONS: Post-traumatic bone defects are one of the most challenging orthopedic conditions to treat. The decision to proceed with reconstruction and the techniques to use should be evaluated on an individual basis, with treatment tailored according to patient and fracture characteristics.

KEY WORDS: Reconstructive surgical procedures; Ilizarov technique; Bone transplantation