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Minerva Oftalmologica 2018 September;60(3):144-9

DOI: 10.23736/S0026-4903.18.01804-4

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: Italian

Dry eye syndrome from tear substitute to homeopathic eye drops

Angelo M. MINNELLA 1, 2 , Valeria PAGLIEI 1, Gloria GAMBINI 1

1 Institute of Ophtalmology, Catholic University of Sacred Heart, Rome, Italy; 2 Fondazione Policlinico A. Gemelli, IRCSS, Rome, Italy



Dry eye syndrome is one of the main disorders reported by the patient during an eye examination.
More recently, the established role of inflammation in the pathogenesis of tear film dysfunction has shifted the focus from artificial tears (necks based on tear film stabilizing substitutes) to active substances in homeopathic dilution, based on extracts from medicinal plants, to ocular organotropism with anti-inflammatory properties.
Although allergic conjunctivitis and dry eye syndrome are normally considered two different clinical entities, there is a growing interest in the temporal and pathogenetic relationship between the two pathological patterns.
Finally, we will talk about the importance of using parcels without preservatives. Several studies have shown that in prolonged therapy preservatives can have a toxic effect on the components of the ocular surface. Already in the 90s studies had shown an anomalous expression of the markers of inflammation of the conjunctival cells of patients exposed to drugs and their preservatives.


KEY WORDS: Dry Eye - Therapy - Preservatives - Personalized medicine

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