ORIGINAL ARTICLE   

Minerva Ginecologica 2018 April;70(2):144-9

DOI: 10.23736/S0026-4784.17.04123-5

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: English

Pregnancy outcomes in women with endometriosis

Tamar TZUR ¹, Adi Y. WEINTRAUB ¹, Orly ARIAS GUTMAN ¹, Yael BAUMFELD ¹, David SORIANO ², Salvatore A. MASTROLIA ^{1, 3} ✉, Eyal SHEINER ¹

¹ Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel; ² Department of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Tel-Aviv University, Ramat Gan, Israel; ³ Department of Obstetrics and Gynecology, Fondazione MBBM, San Gerardo Hospital, University of Milano Bicocca, Monza, Italy

BACKGROUND: The aim of this study was to investigate whether patients with endometriosis who achieved pregnancy have a higher risk for pregnancy complications and adverse perinatal outcomes as compared to patients without endometriosis.
METHODS: The study compared obstetrical and perinatal outcomes of women with and without endometriosis who delivered between 1988-2013 at the Soroka University Medical Center. The study population included 504 deliveries divided into the following groups: 1) women with endometriosis (N.=35); and 2) without endometriosis (N.=467). Endometriosis was diagnosed by laparoscopy or laparotomy. Multiple logistic regression models were used to control for confounders.
RESULTS: No significant increase in obstetrical complications was noted in the endometriosis group, but significantly higher rates of cesarean sections. Perinatal outcomes were comparable between the groups.
CONCLUSIONS: In our population, endometriosis was not found as a risk factor for obstetrical complications or adverse perinatal outcomes. Larger population based cohort studies are needed to clarify the relationship between endometriosis and adverse pregnancy outcomes.

KEY WORDS: Endometriosis - Preeclampsia - Fetal growth retardation - Premature birth - Cesarean section