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Minerva Medica 2020 Jun 22

DOI: 10.23736/S0026-4806.20.06732-4

Copyright © 2020 EDIZIONI MINERVA MEDICA

language: English

Endoscopic surveillance after surgery for colorectal cancer

Leonardo FRAZZONI 1, Marina LA MARCA 1, Valentina DI GIORGIO 1, Liboria LATERZA 1, Franco BAZZOLI 1, Cesare HASSAN 2, Lorenzo FUCCIO 1

1 Gastroenteorlogy Unit, Department of Medical and Surgical Sciences, S.Orsola-Malpighi University Hospital, University of Bologna, Bologna, Italy; 2 Endoscopy Unit, Nuovo Regina Margherita Hospital, Rome, Italy


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Colorectal cancer (CRC) is one of the most common cancers worldwide and its global incidence is rapidly increasing among adults younger than 50 years, especially in the 20-39 age group. Once a curative resection is achieved, surveillance is mandatory. Colonoscopy has a pivotal role aimed at resecting pre-malignant neoplasms and detecting cancer at a curable stage. In the current review, an update on the role of surveillance colonoscopy after CRC is provided, taken into account the most recent international guidelines and evidence published on this issue. In particular, several questions have been answered, why, how and how often colonoscopy should be performed, whether intensive surveillance is more effective than standard surveillance, how endoscopically resected T1 cancer should be followed, the different management existing between colon and rectal cancer, and, finally, how to improve the endoscopic surveillance. In a period of resource constraints, appropriateness will be mandatory, thus understanding how to optimize the role of colonoscopy in the surveillance of patients with a history of CRC is of crucial importance. Improving the quality of colonoscopy and identifying risk factors for recurrent and new-onset CRC, will allow us to individualize the surveillance program while sparing health care cost.


KEY WORDS: Colorectal cancer; Endoscopy; Surveillance

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