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REVIEW  MULTIDISCIPLINARY MANAGEMENT OF ENDOMETRIOSIS 

Minerva Medica 2020 February;111(1):50-61

DOI: 10.23736/S0026-4806.19.06346-8

Copyright © 2019 EDIZIONI MINERVA MEDICA

language: English

Ovulation induction in infertile women with endometriotic ovarian cysts: current evidence and potential pitfalls

Milan TERZIC 1, 2, 3 , Gulzhanat AIMAGAMBETOVA 2, 4, Simone GARZON 5, Gauri BAPAYEVA 2, Talshyn UKYBASSOVA 2, Sanja TERZIC 1, Melanie NORTON 6, Antonio S. LAGANÀ 5

1 Department of Medicine, Nazarbayev University School of Medicine, Astana, Kazakhstan; 2 Clinical Academic Department of Women’s Health, National Research Center of Mother and Child Health, University Medical Center, Astana, Kazakhstan; 3 Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; 4 Department of Biomedical Sciences, Nazarbayev University School of Medicine, Astana, Kazakhstan; 5 Department of Obstetrics and Gynecology, “Filippo Del Ponte” Hospital, University of Insubria, Varese, Italy; 6 Department of Urogynecology, Whittington Hospital, London, UK



Endometriosis is a chronic benign gynecological disease with symptoms that can severely impact quality of life and well-being. Women affected by endometriotic ovarian cyst could have associated infertility problems. Infertility affects 30% to 50% of women with endometriosis. Women with endometriosis are at risk of decreased ovarian reserve, due to the disease pathophysiologic mechanisms. Generally, infertility management include surgical procedure (usually with minimally invasive approach) and ovulation induction with intrauterine insemination or in vitro fertilization. Fertility preservation technologies also include oocyte or embryo freezing and ovarian tissue cryopreservation. Approach to patients with endometriotic cysts still remains controversial, and a multidisciplinary approach is a key factor to achieve the best outcome with appropriate patient counselling. Such management by a multidisciplinary team is a key factor in achieving the successful outcome.


KEY WORDS: Endometriosis; Ovarian cysts; Gynecologic surgical procedures; Fertilization in vitro; Ovulation induction

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