Home > Journals > Minerva Medica > Past Issues > Minerva Medica 2017 August;108(4) > Minerva Medica 2017 August;108(4):341-9



Publication history
Cite this article as


A Journal on Internal Medicine

Indexed/Abstracted in: Current Contents/Clinical Medicine, EMBASE, PubMed/MEDLINE, Science Citation Index Expanded (SciSearch), Scopus
Impact Factor 1,878




Minerva Medica 2017 August;108(4):341-9

DOI: 10.23736/S0026-4806.17.05188-6


language: English

Change gout: the need for a new approach

Leonardo PUNZI

Unit of Rheumatology, Department of Medicine DIMED, Padua University Hospital, Padua, Italy


Gout is the most common form of inflammatory arthropathy and is caused by an excess of uric acid in the blood (hyperuricemia). It is a chronic, debilitating condition that gradually increases in severity and affects an increasing number of people. It has a wide spectrum of clinical manifestations and is related to serious kidney and cardiovascular conditions and to an increased risk of mortality. The negative perception of the disease, historically seen as related to a life of dissipation, has led to underestimating its impact and focusing the attention on the short-term treatment of acute attacks rather than on the long-term management of the condition without, consequently, preventing the most serious complications. The most recent scientific evidence and the increasing understanding of the physio-pathologic mechanisms responsible for hyperuricemia and gout reveal a very different reality, in which gout is a condition which is only minimally affected by lifestyle and mainly by increasingly better identified genetic factors. Appropriate doctor training and patient education, catalyzed by the renewed attention to this disease and to new treatment options which overcome the limits of therapies currently available, will help to break down current barriers to allow for its optimal management.

KEY WORDS: Gout - Joint diseases - Hyperuricemia

top of page

Publication History

Issue published online: June 28, 2017

Cite this article as

Punzi L. Change gout: the need for a new approach. Minerva Med 2017;108:341-9. DOI: 10.23736/S0026-4806.17.05188-6

Corresponding author e-mail