Home > Journals > Minerva Medica > Past Issues > Minerva Medica 2004 December;95(6) > Minerva Medica 2004 December;95(6):529-34

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe PROMO
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Reprints
Permissions

 

ORIGINAL ARTICLES   

Minerva Medica 2004 December;95(6):529-34

Copyright © 2004 EDIZIONI MINERVA MEDICA

language: English

Long term follow-up of bone mineral density in patients with primary biliary cirrhosis

Di Bisceglie A. M., Loyet M., Peters M.


PDF


Aim. Osteodystrophy is a well known complication of cholestatic liver diseases such as primary biliary cirrhosis (PBC), although the factors predisposing to the development of metabolic bone disease and its natural history have not been well studied.
Methods. We followed a cohort of patients, predominantly post-menopausal females, for changes in bone mineral density over a period of up to 8 years.
Results. We found that most patients with PBC have relatively stable lumbar bone density over time, even in the face of progressive liver disease. Only 2 of 22 patients experienced fractures. Both of these patients had low initial bone density measurements.
Conclusion. We recommend that all patients with newly diagnosed PBC undergo bone mineral density measurment so as to identify those at greatest risk of pathological fractures.

top of page