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Minerva Medica 2001 April;92(2):133-6

Copyright © 2001 EDIZIONI MINERVA MEDICA

language: English

Renal involvement in Waldenstrom’s macroglobulinemia. Case report and review of the literature

Nifosì G.


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The author reports a patient with Walden-strom's macroglobulinemia and infiltration of the kidney interstitium with lymphoplasmacytoid cells. In contrast to multiple myeloma, infiltration of the kidney interstitium with lymphoplasmacytoid cells is not a rare event in Waldenstrom's macroglobulinemia at all. Our case reported showed enlargement of the kidney with a diffuse increase in the cortical echogenicity and the presence of hypoechogenic areas scattered throughout the kidney, there was no renal or perirenal masses. The treatment with chlorambucil and prednisone was ineffective, and she has a good response to a polychemotherapy regimen. The role of fine-needle aspiration biopsy performed under ultrasound guidance is emphasized.

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