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Minerva Ginecologica 2020 Nov 30

DOI: 10.23736/S0026-4784.20.04683-3

Copyright © 2020 EDIZIONI MINERVA MEDICA

language: English

Tailoring parametrectomy for early cervical cancer (Stage IA-IIA FIGO): a review on surgical, oncologic outcome and sexual function

Francesco PLOTTI, Fernando FICAROLA , Giuseppe MESSINA, Corrado TERRANOVA, Roberto MONTERA, Federica GUZZO, Carlo DE CICCO NARDONE, Gianmarco ROSSINI, Teresa SCHIRÒ, Alessandra GATTI, Daniela LUVERO, Laura FEOLE, Roberto ANGIOLI

Obstetrics and Gynecology, University Campus Bio-Medico of Rome, Rome, Italy


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INTRODUCTION: Cervical cancer is currently one of the most common cancers afflicting the female population worldwide and in industrialized countries the presence of screening and a specific diagnostic and therapeutic process has favored early diagnosis of cervical cancer. In literature have found that reducing the radicality on the parametria in early cervical cancer (ECC), reduces complications without impacting oncological outcomes, but the data in the literature are not yet clear.
EVIDENCE ACQUISITION: Searching on Pubmed we included 1473 articles from January 1974 to 2020. We identified all the studies that compared different type of radical hysterectomy in the primary surgical treatment of ECC. 16 articles were elected for the review.
EVIDENCE SYNTHESIS: Modified radical hysterectomy (Piver II /Querleu-Morrow Type B) in ECC, if compared to CRH (Piver III / Querleu-Morrow Type C2), is not associated with worse cancer outcome and patient survival, but it is associated with a minor operating time, lower blood loss and minor bladder dysfunction. Nerve sparing radical hysterectomy approach (NSRH/ Querleu-Morrow Type C1) compared to CRH (Piver III / Type C2) in the ECC, with our data we can confirm a noninferiority regarding the oncological outcome.
CONCLUSIONS: Reduced radicality on the parametrium offers positive effects on the quality of life (sexual life and bladder function) of patients without impacting on survival, oncological outcome.


KEY WORDS: Nerve-sparing radical hysterectomy early cervical cancer; Radical hysterectomy early cervical cancer; Sexual function early cervical cancer

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