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MINERVA GINECOLOGICA

A Journal on Obstetrics and Gynecology


Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index


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Minerva Ginecologica 2018 Apr 11

DOI: 10.23736/S0026-4784.18.04232-6

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English

Indications for fertility preservation in women from malignant diseases to benign conditions to age-related fertility decline

Marie-Madeleine DOLMANS 1, 2 , Jacques DONNEZ 3, 4

1 Pôle de Gynécologie, Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain, Brussels, Belgium; 2 Gynecology Department, Cliniques Universitaires Saint Luc, Brussels, Belgium; 3 Université Catholique de Louvain, Brussels, Belgium; 4 Société de Recherche pour l'Infertilité (SRI), Brussels, Belgium


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Oocyte vitrification and ovarian tissue cryopreservation are 2 common fertility preservation options. Oocyte vitrification provides the highest yield for women with benign diseases or those seeking fertility preservation for age-related fertility decline. This technique is also indicated for cancer women if cancer treatment can be post-poned. Ovarian tissue cryopreservation has some specific indications. There is indeed no other alternative for fertility preservation in prepubertal girls, adolescents and cancer women in whom cancer treatment cannot be postponed. This review focuses on the indications for fertility preservation from malignant diseases to benign conditions to age-related fertility decline.


KEY WORDS: Fertility preservation - Oncofertility - Ovarian tissue cryopreservation - Oocyte vitrification - Malignant diseases - Benign diseases - Social reasons

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Publication History

Article first published online: April 11, 2018
Manuscript accepted: April 4, 2018
Manuscript received: March 20, 2018

Cite this article as

Dolmans MM, Donnez J. Indications for fertility preservation in women from malignant diseases to benign conditions to age-related fertility decline. Minerva Ginecol 2018 Apr 11. DOI: 10.23736/S0026-4784.18.04232-6

Corresponding author e-mail

marie-madeleine.dolmans@uclouvain.be