Home > Journals > Minerva Ginecologica > Past Issues > Minerva Ginecologica 2018 April;70(2) > Minerva Ginecologica 2018 April;70(2):220-33



Publication history
Cite this article as


A Journal on Obstetrics and Gynecology

Indexed/Abstracted in: EMBASE, PubMed/MEDLINE, Scopus, Emerging Sources Citation Index




Minerva Ginecologica 2018 April;70(2):220-33

DOI: 10.23736/S0026-4784.17.04164-8


language: Italian

Hydrating cleansing: efficacy and tolerability of new formulations with hyaluronic acid 0.2% for intimate hygiene in the woman in fertile age and menopause

Francesca ALBANI 1, Adriana BONFIGLI 2, Francesca CONSOLARO 3, Luigi RIGANO 4, Monica CAMPISI 3

1 Unit of Endocrinology and Gynecology, Istituti Clinici Scientifici Maugeri, Pavia, Italy; 2 ISPE, Institute of Skin and Product Evaluation, Milan, Italy; 3 Fidia Farmaceutici S.p.A., Abano Terme, Padua, Italy; 4 Rigano Laboratories S.r.l., Milan, Italy


Dehydration of genital areas, known as vaginal dryness, frequently affects woman’s life, from fertile to postmenopausal period, and must be treated with specific products, including proper intimate cleansing. Based on that, two new cleanser formulations, characterized by Hyaluronic Acid 0.2% as main ingredient, have been developed (Hyalo Gyn® Intimo Active and Hyalo Gyn® Intimo Advance), with the aim to provide an effective hydration of the vaginal, vulvar, perianal and anal areas beyond guaranteeing daily intimate hygiene. The two intimate cleansing mousses have been formulated in mousse and differentiated, in terms of ingredients, accordingly to the different physiological conditions and female needs of fertile age and menopause respectively. Clinical trials conducted on women of childbearing age and menopause showed that daily cleansing with these intimate washes promotes hydration of vaginal tissues thanks to the presence of hyaluronic acid. In particular, the cleansing mousse for fertile women gives also a soothing effect, offers antimicrobial protection and a long lasting feeling of freshness. The cleansing mousse for menopausal women provides a freshness sensation, improves elasticity and tonicity and exerts an anti-smell and anti-oxidative effect.

KEY WORDS: Feminine hygiene products - Detergents - Hyaluronic acid

top of page

Publication History

Issue published online: February 2, 2018
Manuscript accepted: October 27, 2017
Manuscript received: October 25, 2017

Cite this article as

Albani F, Bonfigli A, Consolaro F, Rigano L, Campisi M. La detersione idratante: efficacia e tollerabilità di nuove formulazioni a base di acido ialuronico 0,2% per l’igiene intima della donna in età fertile e in menopausa. Minerva Ginecol 2018;70:220-33. DOI: 10.23736/S0026-4784.17.04164-8

Corresponding author e-mail