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A Journal on Obstetrics and Gynecology

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Minerva Ginecologica 2017 December;69(6):587-96

DOI: 10.23736/S0026-4784.17.04082-5


language: English

The current management of deep endometriosis: a systematic review

Marina de PAULA ANDRES 1, Giuliano M. BORRELLI 1, Rosanne M. KHO 2, Mauricio S. ABRÃO 1

1 Division of Endometriosis, Department of Obstetrics and Gynecology, Faculty of Medicine, University of São Paulo, São Paulo, Brazil; 2 Women’s Health Institute, Cleveland Clinic, Cleveland, OH, USA


INTRODUCTION: Endometriosis is a chronic inflammatory disease that affects young women in reproductive age. It has mainly three different clinical presentations: superficial (peritoneal), ovarian (endometriomas) and deep endometriosis (DE). The last one is the most advanced form of the disease, frequently impairing fertility and harming women’s quality of life (QoL).
EVIDENCE ACQUISITION: We conducted a systematic review on the surgical treatment of DE in the last ten years focusing on its benefits to improve QoL and for pain relief as well as related surgical complications.
EVIDENCE SYNTHESIS: Twenty-three studies were included for qualitative analysis. Overall, included studies showed a relevant improvement in QoL as well as in pain scores using specific questionnaires and the ten-point Visual Analogue Scale (VAS) for pain.
CONCLUSIONS: Until further comparative studies regarding medical versus surgical treatment for DE are concluded, currently, surgery is the best option for patients with DE and severe pain (VAS>7).

KEY WORDS: Endometriosis - Surgical procedures, operative - Quality of life - Intraoperative complications

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Publication History

Issue published online: October 24, 2017
Article first published online: May 25, 2017
Manuscript accepted: May 23, 2017
Manuscript received: May 3, 2017

Cite this article as

de Paula Andres M, Borrelli GM, Kho RM, Abrão MS. The current management of deep endometriosis: a systematic review. Minerva Ginecol 2017;69:587-96. DOI: 10.23736/S0026-4784.17.04082-5

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