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Minerva Ginecologica 2016 October;68(5):492-6

Copyright © 2016 EDIZIONI MINERVA MEDICA

language: English

The safety and acceptability of Pipelle endometrial sampling in premenopausal women in comparison to postmenopausal women with abnormal uterine bleeding

Mohamed REZK, Ragab DAWOOD, Alaa MASOOD

Department of Obstetrics and Gynecology, Faculty of Medicine, Menoufia University, Menoufia, Egypt


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BACKGROUND: The aim of this study was to assess the safety and acceptability of Pipelle endometrial sampling in premenopausal women in comparison to postmenopausal women.
METHODS: This was a prospective observational study including a total of 346 patients with abnormal uterine bleeding (AUB) who were divided into two groups, premenopausal group (N.=210) and postmenopausal group (N.=136). Primary outcome was safety and adequacy of Pipelle sampler. Secondary outcome included patients’ acceptability.
RESULTS: Pain scores by Visual Analogue Scale were significantly higher in postmenopausal women compared to premenopausal women (6.5±1.13 versus 4.85±0.86, P<0.001) during Pipelle endometrial sampling. There was also a higher rate of tenaculum use and analgesic requirements with less adequacy of the sample and less acceptability in postmenopausal women (P<0.001).
CONCLUSIONS: Pipelle endometrial sampling is more painful, less adequate and less acceptable in postmenopausal women compared to premenopausal women with AUB. Further larger trials are needed to confirm these findings.

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