Home > Journals > Minerva Ginecologica > Past Issues > Minerva Ginecologica 2014 August;66(4) > Minerva Ginecologica 2014 August;66(4):377-81

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Reprints
Permissions

 

ORIGINAL ARTICLES   

Minerva Ginecologica 2014 August;66(4):377-81

Copyright © 2014 EDIZIONI MINERVA MEDICA

language: English

An alternative approach for the treatment of vaginal atrophy

Quaranta L., Ottolina J., Parma M., Chionna R., Sileo F., Dindelli M., Origoni M., Candiani M., Salvatore S.

Gynecology Department, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, School of Medicine, Milan, Italy


PDF


AIM: The aim of this study was to determine the efficacy of a new topic non-hormonal treatment for postmenopausal women complaining of symptoms of vaginal atrophy.
METHODS: Patients included in the study were prescribed Sinecol gel (AM PHARMA Srl, Vimercate, Monza and Brianza, Italy) application once a day for 20 consecutive days. Sinecol gel is a topic compound for vaginal atrophy containing hyaluronic acid, that is known to improve vaginal elasticity, lactoperoxidase, Xantham gum and glucose oxidase, which have protective and antibacterial action. We evaluated each patient before and after treatment, both subjectively with the “Visual Analogical Scale” (VAS) and objectively with the “Vaginal Health Index” (VHI).
RESULTS: We observed a significant clinical improvement of the subjective and objective assessment of symptoms severity with a p value <0.001 at the end of the treatment compared to baseline.
CONCLUSION: Sinecol gel appears to be an effective and valid non-hormonal alternative to the estrogen therapy for vaginal atrophy.

top of page