Home > Journals > Minerva Ginecologica > Past Issues > Minerva Ginecologica 2003 October;55(5) > Minerva Ginecologica 2003 October;55(5):441-50

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Reprints
Permissions

 

REVIEWS  CURRENT TOPICS IN INFERTILITY 

Minerva Ginecologica 2003 October;55(5):441-50

Copyright © 2003 EDIZIONI MINERVA MEDICA

language: English

Reccurent spontaneous early pregnancy loss and low dose aspirin

Daya S.


PDF


Miscarriage is the most common complication of pregnancy, occurring in 10-15% of pregnant women. Accurate figures on prevalence are not available but it has been estimated that 2-5% of women have 3 or more miscarriages. The lack of methodological rigour in controlled trials of treatment efficacy in women with recurrent miscarriage makes it difficult to estimate the efficacy of treatment for this condition. To date, there is no evidence of improved outcome with aspirin compared to placebo or no treatment. Furthermore, animal data and limited human data suggest that prenatal use of aspirin may be associated with increased bleeding tendency, congenital malformations and cognitive and behavioural defects in the offspring. Seen and considered the lack of efficacy of low-dose aspirin and the potential for harm to the female and her offspring, the practice of recommending aspirin to women with recurrent miscarriage should be discountinued.

top of page