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REVIEW
Minerva Endocrinology 2023 March;48(1):88-105
DOI: 10.23736/S2724-6507.22.03652-1
Copyright © 2023 EDIZIONI MINERVA MEDICA
language: English
Vitamin D: review of physiology and clinical uses
Rainer BURKHARDT ✉
Private Practitioner, Oldenburg, Germany
Interest in vitamin D has increased within the scientific community due to the impact of osteoporosis in the aging population. Vitamin D receptors are present in many tissues and low vitamin D status has been associated with many diseases in observational studies. There was hope that enhanced vitamin D provision might help prevent and treat some widespread disorders. Some of these hopes have been refuted by the results of recent large and well-conducted randomized trials. This review provides an overview of the basic physiology of vitamin D and an update on the evidence base for its clinical applications.
KEY WORDS: Vitamin D; Physiology; Prevention and control