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REVIEW  SUBCLINICAL ENDOCRINE DISEASE: OLD AND NEW CLINICAL SCENARIOS 

Minerva Endocrinology 2021 September;46(3):238-42

DOI: 10.23736/S2724-6507.20.03176-4

Copyright © 2020 EDIZIONI MINERVA MEDICA

language: English

Subclinical hypothyroidism

Jessica CHBAT 1, Shereen EZZAT 1, Giampaolo PAPI 2

1 Endocrine Oncology Site Group, Princess Margaret Cancer Center, Toronto, Canada; 2 Unit of Endocrinology, Northern Area, USL Modena, Modena, Italy



Subclinical hypothyroidism (i.e. a condition characterized by serum TSH concentrations above the normal reference range in the presence of normal serum T4 levels) affects 4 to 20% of the population living in iodine-sufficient areas. The present work reviewed the clinical challenges regarding the signs and symptoms possibly related to subclinical hypothyroidism and the most recent guideline recommendations to treatment.


KEY WORDS: Hypothyroidism; Thyroid diseases; Diagnosis; Therapeutics

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