REVIEWS   

Minerva Endocrinologica 2016 March;41(1):122-37

Copyright © 2016 EDIZIONI MINERVA MEDICA

language: English

Pre-existing diabetes in pregnancy

Suja PADMANABHAN ^{1, 2}, Monica ZEN ³, Vincent LEE ^{2, 4, 5}, Ngai W. CHEUNG ^{1, 2} ✉

¹ Department of Diabetes and Endocrinology, Westmead Hospital, Sydney, Australia; ² School of Medicine, University of Sydney, Sydney, Australia; ³ Department of Obstetrics and Gynecology, Westmead Hospital, Sydney, Australia; ⁴ Department of Renal Medicine, Westmead Hospital, Sydney, Australia; ⁵ Centre for Transplant and Renal Research, Westmead Millennium Institute, Sydney, Australia

The incidence of type 1 and type 2 diabetes amongst women of reproductive age is increasing worldwide. Despite recent advances in treatment options for diabetes outside of pregnancy, women still have a significantly increased risk of adverse obstetric outcomes including perinatal death and congenital malformation, compared to the non-diabetic population. An understanding of the physiological changes during pregnancy, management, early detection and prevention of complications and pre-pregnancy care, specific to women with pre-existing diabetes, is important in improving health outcomes in this growing group of women. This review particularly focuses on areas where there have been recent developments or controversy.