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A Journal on Endocrine System Diseases

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Minerva Endocrinologica 2018 Feb 13

DOI: 10.23736/S0391-1977.18.02780-3


language: English

A clinical Audit: diagnostic and epidemiological evaluation of the Adrenal Incidentaloma (AI)

Vincenzo NUZZO 1 , Tiziana ATTARDO 2, Giuseppe AUGELLO 2, Davide BRANCATO 3, Salvatore CAMERLINGO 4, Clelia CANALE 5, Federica CORETTI 1, Alessandro FRANCO 6, Francesco GIACOMETTI 4, Maurizio GAMBACORTA 7, Massimo LORENO 8, Ada MAFFETTONE 9, Vincenzo PROVENZANO 3, Alfonso ZUCCOLI 1

1 UOSD Endocrinologia, Malattie del Ricambio e della Nutrizione Umana, Presidio Ospedaliero del Mare, Naples, Italy; 2 Presidio Ospedaliero Barone Lombardo, Canicattì, Agrigento, Italy; 3 Presidio Ospedaliero Partinico, Palermo, Italy; 4 Presidio Ospedaliero San Gennaro, Naples, Italy; 5 Presidio Ospedaliero Bianchi Melacrino Morelli, Reggio Calabria, Italy; 6 Presidio Ospedaliero Parodi Delfino Colleferro, Rome, Italy; 7 Presidio Ospedaliero Media Valle del Tevere, Todi, Perugia, Italy; 8 Presidio Ospedaliero Avola Noto, Siracusa, Italy; 9 Azienda Ospedaliera Monaldi, Naples, Italy


Audit is a clinical instrument of government characterized by a whole process of evaluation inter pares to improve medical behaviors in the clinical practice. Different endocrinopathies are underestimated in the clinical and diagnostics practice but they can be a real problem in patients admitted in the departments of Internal Medicine. The Adrenal Incidentaloma (AI) is an accidental discovery with an incidence equal to 4% in radiologic studies but it’s rarely considereted in the internal disorders. In the departments of Internal Medicine are hospitalized each year approximately 1.450.000 patients and 58.000 about them show a surrenalic lesion identified with CT or MRI as Adrenal Incidentaloma. Through a search in the radiological archives, were reviewed all abdominal CT performed in the year 2012 in 8 departments of Internal Medicine of 8 Italian public hospitals. They also examined all medical records of these patients to value clinical management of the adrenal masses and the real incidence of the Adrenal Incidentaloma. Distribution of patological results show an important incidence about Adrenal Incidentaloma in Italian patients although this pathology is represented as a rare disease and its clinical and economic burden are significant. Many questions remain unanswered as the association between duration and severity of the disease, morbidity and how the dimensions affecting it. These results need to be supported by important studies with long follow-up to realize an easy diagnosis. The results of this Audit confirm the real incidence of this pathology in the internistic patients and the final target is to implement changes about therapeutic diagnostic patway of the hospital patients in the Internal Medicine Departments.

KEY WORDS: Adrenal incidentaloma - Asymptomatic masses - Clinical audit - Differential diagnosis

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Publication History

Article first published online: February 13, 2018
Manuscript accepted: January 29, 2018
Manuscript received: November 12, 2017

Cite this article as

Nuzzo V, Attardo T, Augello G, Brancato D, Camerlingo S, Canale C, et al. A clinical Audit: diagnostic and epidemiological evaluation of the Adrenal Incidentaloma (AI). Minerva Endocrinol 2018 Feb 13. DOI: 10.23736/S0391-1977.18.02780-3

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