Home > Journals > Minerva Endocrinologica > Past Issues > Minerva Endocrinologica 2010 June;35(2) > Minerva Endocrinologica 2010 June;35(2):47-52

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe PROMO
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Reprints
Permissions

 

ORIGINAL ARTICLES   

Minerva Endocrinologica 2010 June;35(2):47-52

Copyright © 2010 EDIZIONI MINERVA MEDICA

language: English

Preoperative PTH as a marker of risk for post-thyroidectomy hypocalcemia

Del Rio P., Sommaruga L., Bezer L., Arcuri M. F., Cataldo S.,Ceresini G., Sianesi M.

1 Department of Surgical Science, General Surgery and Organ Transplantation, Parma University Hospital, Parma, Italy; 2 Unit of Endocrinology, Parma University Hospital, Parma, Italy; 3 Unit of Geriatrics Endocrinology, Parma University Hospital, Parma, Italy


PDF


AIM: There are no common guidelines to identify the population at risk to develop hypocalcemia preoperatively or early in the postoperative course in thyroidectomized patients, therefore the authors suggest to examine the PTH value preoperatively.
METHODS: We divided 391 patients in two groups according to the preoperative PTH level (normal, £72 pg/mL vs. increased >73 pg/mL).
RESULTS: In 92/391 cases (23.52%) preoperative PTH was increased (mean PTH level 112.4±24.8 pg/mL; normal range 12-72 pg/mL). Out of these, 43 (46.7%) had hypocalcaemia postoperatively. In 18 out of the 43 patients clinical hypocalcemia also developed. The mean follow-up was of 148±13 days. Of the 299 patients with normal preoperative PTH, 127 (42.47%) developed postoperative hypocalcemia (mean calcium level 7.4±0.33 mg/dL). In 30 patients it was also clinically evident. The difference in terms of incidence of symptomatic hypocalcemia was statistically significant (increased preoperative PTH 19.5% vs. normal preoperative PTH 10.03% , P=0.036).
CONCLUSION: All candidates to thyroidectomy should be investigated for preoperative PTH abnormalities.

top of page