Home > Journals > Minerva Endocrinologica > Past Issues > Minerva Endocrinologica 2002 March;27(1) > Minerva Endocrinologica 2002 March;27(1):7-20

CURRENT ISSUE
 

JOURNAL TOOLS

eTOC
To subscribe PROMO
Submit an article
Recommend to your librarian
 

ARTICLE TOOLS

Reprints
Permissions

 

REVIEWS   

Minerva Endocrinologica 2002 March;27(1):7-20

Copyright © 2002 EDIZIONI MINERVA MEDICA

language: English

The cell cycle in steroid hormone regulated proliferation and differentiation

Amanatullah D. F., Zafonte B. T., Pestell R. G.


PDF


Steroid hormones mediate pleiotropic cellular processes involved in metabolism, cellular proliferation, and differentiation. The ability of the cell to respond to its hormonal environment is transduced by nuclear receptors (NRs) that bind both hormone and DNA. Hence, NRs represent a link between the external hormonal milieu and the genes that control cell physiology. Therefore, understanding the effects of steroid hormones on proliferation and differentiation requires a knowledge of the cell cycle, the interaction of NRs at the level of transcription, and the potential areas of cross-talk between these two.

top of page