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Minerva Dental and Oral Science 2021 Jun 15

DOI: 10.23736/S2724-6329.21.04543-5

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

Noninvasive in vivo imaging of oral mucosa: state-of-the-art

Fausto FIORI 1, Rosario RULLO 1, Maria CONTALDO 1 , Francesco INCHINGOLO 2, Antonio ROMANO 1

1 Multidisciplinary Department of Medical Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, Naples, Italy; 2 Section of Dental Medicine, Department of Interdisciplinary Medicine, University of Bari Aldo Moro, Bari, Italy


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Technological development has interested most of the dentistry’s branches leading to the use of other medical technologies non previously involved in dental practice. This study aims to evaluate the potential role of non-invasive imaging techniques in oral pathology workflow. Optical coherence tomography has been described by several authors as a promising aid for differential diagnosis of autoimmune diseases and to detect epithelial subversion of the oral mucosa before the clinical manifestation of oral mucositis. High-frequency ultrasound offers the chance to assess lesional dimensions both in benign and malignant lesions with a high dimensional reliability compared with histopathology. Reflectance confocal microscopy seems to be helpful in the early detection of cytological changes due to its high resolution, suggesting a more interesting role in the analysis of malignant lesions. The study presented highlighted the potential role of noninvasive in vivo imaging although further studies are needed for the further validation of these techniques.


KEY WORDS: Imaging; Oral mucosa; In vivo diagnosis

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