ORIGINAL ARTICLE   

Minerva Dental and Oral Science 2022 February;71(1):31-8

DOI: 10.23736/S2724-6329.21.04606-4

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

Efficacy of bioactivated anticalculus toothpaste on oral health: a single-blind, parallel-group clinical study

Edoardo BRAUNER ¹, Michele DI COSOLA ², Mariateresa AMBROSINO ², Angela P. CAZZOLLA ², Mario DIOGUARDI ², Riccardo NOCINI ³, Skender TOPI ⁴, Antonio MANCINI ⁵, Maria E. MAGGIORE ⁵, Salvatore SCACCO ⁶, Lucrezia BOTTALICO ⁷, Annarita MALCANGI ⁸, Stefania CANTORE ⁵ ✉

¹ Department of Oral and Maxillo-Facial Sciences, Sapienza University, Rome, Italy; ² Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy; ³ Section of Ear Nose and Throat (ENT), Department of Surgical Sciences, Dentistry, Gynecology and Pediatric, University of Verona, Verona, Italy; ⁴ School of Technical Medical Sciences, A. Xhuvani University, Elbasan, Albania; ⁵ Interdisciplinary Department of Medicine, University of Bari Aldo Moro, Bari, Italy; ⁶ Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy; ⁷ Interdepartmental Research Center for Pre-Latin, Latin and Oriental Rights and Culture Studies (CEDICLO), University of Bari Aldo Moro, Bari, Italy; ⁸ ASL BAT, Trani, Italy

BACKGROUND: Current epidemiologic studies have confirmed the widespread presence of calculus in teenagers and adults of all ages. Among the multiple anticalculus strategies that have been proposed over the years inhibition of crystal growth has been the most attractive. Current formulations in anticalculus toothpastes and mothwash, utilize either hydroxyapatite or various pyrophosphate combinations. This study aimed to analyze the efficacy of an anticalculus tooth paste in combination or not with a mouth rinse.
METHODS: Patients (totally 40) used a pyrophosphate-based toothpaste containing tetrapotassium pyrophosphate, pentasodium triphosphate, xylitol, hydroxyapatite, citric acid, and calcium carbonate (group A) in combination, with a mouth rinse containing an association of pentasodium triphosphate, tetrapotassium pyrophosphate and citric acid (group B). A range of parameters were measured for: saliva pH, Volpe Manhold Calculus Index (VMI), Gingival Index (GI), and Plaque Index (PI).
RESULTS: The test mouth rinse group B showd reductions in VMI, GI, PI, and increases in pH levels, after using the combination of toothpaste and mouth rinse. No changes in the mucosa or teeth were observed in both groups. Patients perceived that the comitation of products was more effective.
CONCLUSIONS: The results from the three-month calculus examination indicated that both the tested products, modified positively clincal parameters and salivary pH. Moreover, the use of the tested products was not associated with any adverse effects.

KEY WORDS: Oral health; Dental health services; Periodontal Index