CASE REPORT   

Minerva Stomatologica 2002 April;51(4):151-6

Copyright © 2002 EDIZIONI MINERVA MEDICA

language: English, Italian

Stevens-Johnson syndrome presumably induced by bromhexine. A case report

Cafasso A., Rao F., Mucciarone L., Ambrosino Di Miccio S.

The Stevens-Johnson syndrome is a serious form of erythema multiforme, an acute inflammatory pathology with an autoimmune pathogenesis. Its etiology is unknown, although it is thought to have multifactorial causes; nonetheless, many drugs are thought to induce such an immune response. The clinical symptomatology is mainly muco-cutaneous, with a remarkable oral involvement. The authors describe here a case of Stevens-Johnson syndrome involving the ocular, oral, and genital areas, presumably induced by the bromhexine administered to the patient for a viral syndrome.