REVIEWS   

Minerva Cardioangiologica 2008 December;56(6):671-92

Copyright © 2008 EDIZIONI MINERVA MEDICA

Hypertrophic cardiomyopathy: individualized therapy for a heterogeneous disease

Sherrid M. V., Sirak T.

Hypertrophic Cardiomyopathy Program and the Echocardiography Laboratory Division of Cardiology, Department of Medicine St. Luke’s, Roosevelt Hospital Center Columbia University College of Physicians and Surgeons New York City, NY, USA

It is now 50 years since the modern description of hypertrophic cardiomyopathy (HCM). The initial descriptions foretold the current efforts towards sudden death prevention, alleviation of heart failure symptoms and angina, relief of left ventricular outflow tract obstruction, preparticipation athletic screening, family screening and genetic testing. The authors review the salient features of HCM, focusing on therapeutic strategies to manage its symptoms and attempts to prevent sudden death.