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A Journal on Heart and Vascular Diseases

Official Journal of the Italian Society of Angiology and Vascular Pathology
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Minerva Cardioangiologica 2018 Mar 15

DOI: 10.23736/S0026-4725.18.04658-3


language: English

Principles of hemodynamic for mechanical circulatory support: patho-physiological key aspects of assisted PCI

Eloisa BASILE, Giulio RUSSO, Antonio M. LEONE

Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy


It is essential to understand the pathophysiology of cardiogenic shock and the possible deterioration of contractile function during high-risk PCI in order to select those patients who could benefit from mechanical support thus choosing the most suitable device in every situation. Percutaneous Ventricular Assist Devices (pVAD) provide hemodynamic support by improving cardiac output and mean arterial pressure, but their specific features result in different hemodynamic effects and degrees of myocardial ischemic protection and LV unloading. These features, together with ease of use, specific contraindications and individual risk of complications, must be taken into account in the evaluation and selection of the device. Ai of this review is to illustrate the principles of left ventricular mechanic, including the pressure- volume loop analysis, in order to better understand, to quantify the different hemodynamic effects of pVAD supports and to explain the key pathophysiological aspects of assisted PCI.

KEY WORDS: Percutaneous ventricular assist devices - Mechanical circulatory support - Assisted PCI

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Publication History

Article first published online: March 15, 2018
Manuscript accepted: March 9, 2018
Manuscript received: March 3, 2018

Cite this article as

Basile E, Russo G, Leone AM. Principles of hemodynamic for mechanical circulatory support: patho-physiological key aspects of assisted PCI. Minerva Cardioangiol 2018 Mar 15. DOI: 10.23736/S0026-4725.18.04658-3

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