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MINERVA CARDIOANGIOLOGICA

A Journal on Heart and Vascular Diseases


Official Journal of the Italian Society of Angiology and Vascular Pathology
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Minerva Cardioangiologica 2018 Feb 01

DOI: 10.23736/S0026-4725.18.04614-5

Copyright © 2018 EDIZIONI MINERVA MEDICA

language: English

How the functional assessment of culprit and non culprit lesions may improve stratification and treatment of STEMI patients

Gianluca CAMPO 1, 2 , Francesco GALLO 1, Giulia BUGANI 1, Rita PAVASINI 1, Massimo FINESCHI 3

1 Cardiovascular Institute, Azienda Ospedaliero-Universitaria di Ferrara, Cona, Ferrara, Italy; 2 Maria Cecilia Hospital, GVM Care & Research, E.S: Health Science Foundation, Cotignola, Ravenna, Italy; 3 Department of Cardiovascular Diseases, University Hospital Santa Maria alle Scotte, Siena, Italy


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Reperfusion therapy of the infarct-related artery (IRA) with primary percutaneous coronary intervention (pPCI) is the cornerstone for the treatment of patients with ST-elevation myocardial infarction (STEMI). However, up to 30% of STEMI patients present a multi-vessel coronary artery disease. Several methods are now available for the assessment of functional severity of a coronary stenosis both for IRA and non culprit coronary lesions. The functional assessment of the IRA has mainly a prognostic implication in terms of major adverse cardiovascular events (MACEs), recovery of left ventricular function and evaluation myocardial viability. Conversely, the functional assessment of the non-culprit coronary lesions has a fundamental role to guide staged revascularization. The aim of this review is to revise the most validated methods to perform the functional assessment of both culprit and non-culprit lesion in ST-elevation myocardial infarction.


KEY WORDS: FFR - IMR - CFR - Culprit lesion - STEMI

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Publication History

Article first published online: February 01, 2018
Manuscript accepted: January 29, 2018
Manuscript received: January 9, 2018

Cite this article as

Campo G, Gallo F, Bugani G, Pavasini R, Fineschi M. How the functional assessment of culprit and non culprit lesions may improve stratification and treatment of STEMI patients. Minerva Cardioangiol 2018 Feb 01. DOI: 10.23736/S0026-4725.18.04614-5

Corresponding author e-mail

cmpglc@unife.it