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Minerva Cardioangiologica 2011 February;59(1):101-8

Copyright © 2011 EDIZIONI MINERVA MEDICA

language: English

Iloprost in the management of peripheral arterial disease in patients with diabetes mellitus

Piaggesi A., Vallini V., Iacopi E., Tedeschi A., Scatena A., Goretti C., Rizzo L.

Sezione Piede Diabetico, Unità Operativa Malattie del Metabolismo e Diabetologia, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italia


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Diabetic complications in the lower extremities, especially those secondary to diabetic macroangiopathy, have increasingly become a clinical emergency, given the high prevalence and progression of the disease. Until recently, the only approach to treating advanced stage disease was medical therapy and major amputation; however, the advent of revascularization procedures has radically improved the prognosis of patients with critical lower limb ischemia. In this setting, iloprost holds a dual position: as first-choice therapy in patients ineligible for revascularization and as complementary therapy in candidates for surgical or endovascular revascularization.

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