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Minerva Cardioangiologica 2002 December;50(6):673-82

Copyright © 2002 EDIZIONI MINERVA MEDICA

language: English, Italian

Diagnosis of coronary artery disease based on blood pool radioisotope angiography at rest

Indovina A.


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Background. The author wanted to determine which of 3 parameters (global left ventricular ejection, regional left ventricular ejection fraction, or isocontours together with peak filling rate and time of peak filling rate) measured with blood pool radioisotope angiography at rest was sufficient to permit diagnosis of coronary artery disease.
Methods. Thirty-one patients with coronary artery disease and 11 hypertensive patients without coronary heart disease were assessed with blood pool radioisotope angiography using a computerized large-field g camera.
Results. Of the 3 parameters measured, only assessment of isocontours with peak filling rate and time of peak filling rate provided sufficient information for establishing a diagnosis of coronary artery disease. In contrast, measurement of global left ventricular ejection provided equivocal data, as did that of regional left ventricular ejection fraction.
Conclusions. In combination with peak filling rate and time of peak filling rate, measurement of isocontours by blood pool radioisotope angiography at rest provided sufficient information for establishing a diagnosis of coronary artery disease.

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