APPLICATIONS OF PEPTIDES NUCLEIC ACIDS (PNA) IN MOLECULAR MEDICINE AND BIOTECHNOLOGY 

Minerva Biotecnologica 1999 September;11(3):227-34

Copyright © 1999 EDIZIONI MINERVA MEDICA

language: English

Microarray technology in molecular diagnosis and gene expression studies

De Bellis G. ¹, Battaglia C. ², Salani G. ², Rossi Bernardi L. ²

¹ Consiglio Nazionale delle Ricerche, Istituto di Tecnologie Biomediche Avanzate, Università degli Studi di Milano; ² Dipartimento di Scienze e Tecnologie Biomediche LITA, Segrate, Italy

This ­review ­deals ­with the ­advent of the so ­called DNA micro­ar­rays, ­also ­named DNA ­chips, ­which it is pre­sumed ­will rev­o­lu­tionise the prac­tice in ­genomic anal­ysis in the ­next few ­years. We ­will ­review not ­only cur­rent lit­er­a­ture, sur­veyed up to ­August 1999, but ­also ­present the ­most inter­esting Web ­resources and ­give ­notice of ­some inter­na­tional and ­national ­efforts for the devel­op­ment and appli­ca­tion of ­this tech­nology.