SPECIAL ARTICLE   

Minerva Biotechnology and Biomolecular Research 2021 September;33(3):157-65

DOI: 10.23736/S2724-542X.21.02765-8

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

A contemporary insight into SARS-CoV-2 pathophysiology, retrieved threat of mutants and prospect of vaccine development

Rasmita DASH, Sujata MOHAPATRA ✉

School of Pharmaceutical Sciences, Department of Pharmaceutics, Siksha ‘O’ Anusandhan (Deemed to be University), Kalinganagar, Bhubaneswar, India

The COVID-19 pandemic has conceived a monstrous threat among the population. Here we portray some of the recent studies on COVID-19 which may supply bases for future research. This review brings a spotlight on the mode of transmission, pathophysiology, genetic structure, mutants of SARS-CoV-2, progress on the vaccination and some recent peculiar disguisable facts about the novel coronavirus 2019. Major scrutiny has been prepared on the new strains of SARS-CoV-2 and also a critical brief review on the ongoing vaccine research strategy and vaccine progress has been added further to that. Being in research this collection of data could have some advantageous response in the development of vaccines and understanding the actual behavior of SARS-CoV-2 in the research territory.

KEY WORDS: SARS-CoV-2; Physiopathology; Genetic structures; Vaccines