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A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care

Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
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Minerva Anestesiologica 2017 Dec 13

DOI: 10.23736/S0375-9393.17.12330-8


language: English

Neuromuscular block in laparoscopic surgery

Thomas FUCHS-BUDER 1, Edoardo DE ROBERTIS 2 , Laurent BRUNAUD 3

1 Département d’Anesthésie-Réanimation, Université de Lorraine, CHU de Nancy Brabois, Vandoeuvre-les-Nancy, France; 2 Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”, Naples, Italy; 3 Service de Chirurgie Digestive, Hépatobiliaire, Endocrinienne, et Carcinologique, Unité Multidisciplinaire de la Chirurgie de L'obésité du CHU de Nancy, Unité Inserm U954, Faculté de Médecine, Université de Lorraine, CHU de Nancy Brabois, Lorraine, France


BACKGROUND: There is an increased interest in the current literature to evaluate the potential clinical benefit of a sustained deep neuromuscular blockade ( i.e. a post-tetanic count ≤ 3) during various laparoscopic surgical procedures. This deep block concept represents a new area of clinical research, which concerns both, anesthesiologists and surgeons.
METHODS: We reviewed a selection of recent publications about the indications and the potential benefits of a maintained deep neuromuscular blockade during different laparoscopic procedures. Moreover, the contribution of the diaphragmatic relaxation to the overall surgical conditions is highlighted, also.
RESULTS: There is convincing evidence that deep neuromuscular blockade compared to moderate neuromuscular block improves surgical conditions, at least for the following surgical procedures: laparoscopic cholecystectomy, prostatectomy, nephrectomy and laparoscopic bariatric surgery. Moreover, first evidence suggests that deep block may reduce perioperative surgical complications and improve patient’s outcome.
CONCLUSIONS: There are situations during laparoscopic surgery where a better communication between surgeon and anesthesiologist may improve patient’s outcome. Moreover, clinical research has now to identify which additional procedures and type of patients may benefit most from this new deep block concept and ultimately, whether the implementation of a routine deep neuromuscular block may affect patient’s outcome.

KEY WORDS: Laparoscopic surgery - Neuromuscular blockade - Deep block - Diaphragm - Sugammadex - Train-of-four - Post-tetanic count - Patient outcome

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Publication History

Article first published online: December 13, 2017
Manuscript accepted: November 30, 2017
Manuscript revised: November 6, 2017
Manuscript received: July 28, 2017

Cite this article as

Fuchs-Buder T, De Robertis E, Brunaud L. Neuromuscular block in laparoscopic surgery. Minerva Anestesiol 2017 Dec 13. DOI: 10.23736/S0375-9393.17.12330-8

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