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MINERVA ANESTESIOLOGICA

A Journal on Anesthesiology, Resuscitation, Analgesia and Intensive Care


Official Journal of the Italian Society of Anesthesiology, Analgesia, Resuscitation and Intensive Care
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Minerva Anestesiologica 2017 Oct 12

DOI: 10.23736/S0375-9393.17.12033-X

Copyright © 2017 EDIZIONI MINERVA MEDICA

language: English

Bispectral index (BIS) and non-BIS anesthetic protocols on postoperative recovery outcomes: a systematic review and meta-analysis

Min-Hsien CHIANG 1 , Shao-Chun WU 1, Shih-Wei HSU 2, Jo-Chi CHIN 1, 3

1 Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan; 2 Department of Radiology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan; 3 Chia-Nan University of Pharmacy and Science, Tainan, Taiwan


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BACKGROUND: The study aimed to compare bispectral index (BIS) and non-BIS anesthetic protocols on postoperative recovery outcomes.
METHODS: Medline, PubMed, Cochrane, EMBASE, and Google Scholar databases were searched until January 21, 2016.
RESULTS: Twenty-six studies were included with a total of 9537 patients. BIS monitoring was significantly associated with shorter time to eye opening (P=0.001), time to extubation (P<0.001), and time to orientation (P=0.002) compared with non-BIS monitoring. No difference between groups was seen with respect to hypoxemia, postoperative nausea and vomiting (PONV), time to oral fluid intake, and length of post-anesthesia care unit (PACU) stay (P values ≥0.185).
CONCLUSIONS: The use of BIS-monitoring is superior to non-BIS monitored anesthesia in terms of shorter time to extubation, eye-opening, and orientation. BIS monitor may be considered a safe and effective method for monitoring depth of anesthesia during surgery.


KEY WORDS: Anesthesia - Bispectral index - Eye opening - Extubation - Recovery - Postoperative

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Publication History

Article first published online: October 12, 2017
Manuscript accepted: October 10, 2017
Manuscript revised: September 27, 2017
Manuscript received: March 2, 2017

Cite this article as

Chiang MH, Wu SC, Hsu SW, Chin JC. Bispectral index (BIS) and non-BIS anesthetic protocols on postoperative recovery outcomes: a systematic review and meta-analysis. Minerva Anestesiol 2017 Oct 12. DOI: 10.23736/S0375-9393.17.12033-X

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ducky0421@gmail.com