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Minerva Anestesiologica 2021 September;87(9):1042-8

DOI: 10.23736/S0375-9393.21.15625-1

Copyright © 2021 EDIZIONI MINERVA MEDICA

language: English

Corticosteroids in patients with COVID-19: use and misuse

Giovanni M. ROMANO 1 , Tullio CAFIERO 1, Antonio FRANGIOSA 1, Edoardo DE ROBERTIS 2

1 Department of Anesthesia and Intensive Care Unit, Cardarelli Hospital, Naples, Italy; 2 Department of Medicine and Surgery, University of Perugia, Perugia, Italy



Corticosteroids use in severe and critical COVID-19 patients is recommended by international guidelines, as they reduce mortality. However, the use outside of these indications could be harmful and should be discouraged. The scope of this brief review is to examine the beneficial mechanisms of corticosteroids treatment in COVID-19 and when they should be adopted.


KEY WORDS: COVID-19; Severe acute respiratory syndrome; Pneumonia; Adrenal cortex hormones; Dexamethasone

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