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Minerva Anestesiologica 2020 November;86(11):1135-42
DOI: 10.23736/S0375-9393.20.14456-0
Copyright © 2020 EDIZIONI MINERVA MEDICA
language: English
Hands-free induction of general anesthesia: a randomised pilot study comparing usual care and high-flow nasal oxygen
Benjamin TREMEY 1, Pierre SQUARA 2, Hugues DE LABARRE 3, 4, Sabrina MA 3, 4, Marc FISCHLER 3, 4 ✉, Jean-Dominique LAWKOUNE 1, Morgan LE GUEN 3, 4
1 Department of Anesthesiology, Ambroise Paré Medico-Surgical Center, Neuilly sur Seine, France; 2 Unit of Research, Ambroise Paré Medico-Surgical Center, Neuilly sur Seine, France; 3 Department of Anesthesiology, Foch Hospital, Suresnes, France; 4 University of Versailles Saint-Quentin-en-Yvelines, Versailles, France
BACKGROUND: The induction of general anesthesia is preceded by face mask preoxygenation and oxygen delivery during intubation (peroxygenation). High-flow nasal oxygen (HFNO) may be an effective alternative.
METHODS: In this multicenter randomized controlled study, adults undergoing general anesthesia with oral intubation were included, provided written consent, and were assigned to the control group (face mask) or experimental group (HFNO). The primary objective was to validate HFNO as a safe and efficient technique for preoxygenation and peroxygenation. The main outcome was the risk of oxygen desaturation (SpO
RESULTS: Among 68 eligible patients, 61 completed the study (31 in the face mask group and 30 in the HFNO group). The patient characteristics were comparable between groups. A decrease in SpO
CONCLUSIONS: HFNO provides a hands-free induction of general anesthesia and yields adequate preoxygenation and peroxygenation, with a significant improvement in the quality of care.
KEY WORDS: Anesthesia, endotracheal; Oxygen; Intubation