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Minerva Anestesiologica 2011 April;77(4):468-9

Copyright © 2011 EDIZIONI MINERVA MEDICA

language: English

Vascular injury following accidental intra-arterial injection of clindamycin: adverse drug reaction report

Lehavi A. ¹, Sandler A. ¹, Netzer A. ², Katz Y. S. ^{1, 3} ✉

¹ Department of Anesthesiology, Rambam Health Care Campus, Haifa, Israel; ² Ear, Nose and Thought and Head and Neck Surgery, Rambam Health Care Campus, Haifa, Israel; ³ Ruth and Bruce Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel

Clindamycin in a commonly used antibiotic, considered safe for oral, intravenous and intra-arterial use. We present a case of a patient that received an inadvertent injection clindamycin 600 mg in 4 mL through a radial arterial line. The patient presented signs and symptoms of vascular occlusion and despite aggressive pharmacological and medical treatment developed massive and severe tissue injury.